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Feb 18, 2020 · Alli is a 60-milligram, over-the-counter version of orlistat (Xenical), a 120-milligram prescription drug. Both Alli and Xenical are meant to be used as part of a weight-loss plan that includes a low-calorie, low-fat diet and regular physical activity. Alli is approved for use in adults 18 and older who have a body mass index (BMI) of 25 or more.
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